Do you have a family history of breast cancer?
Ask yourself the question. The answer could help you be ready against hereditary cancer.
What is a family history of breast or ovarian cancer?
To understand if breast or ovarian cancer runs in your family, look at your whole family history, including your father’s side. Breast or ovarian cancer risk isn’t just passed from mother to daughter or son. A father can also pass it on to his daughter or son.
You could have an inherited risk if*:
- You or a family member (mother’s or father’s side) were diagnosed with breast cancer at age 50 or younger
- You or a family member were diagnosed with ovarian cancer at any age
- You have a male family member with breast cancer at any age
- You have Ashkenazi Jewish ancestry, and a personal or family history of an HBOC- associated† cancer at any age
- There are two breast cancers in the same person or on the same side of the family
- You or a family member were diagnosed with triple negative breast cancer at any age
- There is pancreatic cancer and an HBOC- associated† cancer on the same side of the family
- You have a previously identified BRAC1 or BRAC2 mutation in your family
Most hereditary breast and ovarian cancer occurs because of a mutation in either the BRAC1 or BRAC2 genes.
If you have a BRAC gene mutation, you could have up to an 87% risk of breast cancer and up to a 44% risk of ovarian cancer in your lifetime.
Understanding if breast or ovarian cancer runs in your family is important. Research shows that early detection—along with taking certain steps—can reduce your risk of developing hereditary cancer.
*Assessment criteria based on medical society guidelines. For these individual medical society guidelines go to www.myriadtests.com/patient_guidelines.
†HBOC-associated cancers include breast, ovarian, and pancreatic cancer
What does it mean to have a family history of breast or ovarian cancer?
Hereditary breast and ovarian cancer syndrome is an inherited condition that causes an increased risk for breast and ovarian cancer.
Mutations in the BRAC1 and BRAC2 genes account for the vast majority of hereditary breast and ovarian cancers. Knowing if you have a BRAC gene mutation can help you to know your risk of hereditary cancer and inform your family of their potential risk of hereditary cancer.
Important facts and figures about BRAC mutationsWomen with a BRAC mutation have:
- Up to a 50% risk of developing breast cancer by age 50
- Up to an 87% risk of developing breast cancer by age 70
- Up to a 64% risk of developing a second breast cancer
- Up to a 44% chance of developing ovarian cancer by age 70
- Certain BRAC mutations are more common among people of Ashkenazi Jewish descent
- BRAC mutations also increase the risk for other cancers in both men and women, including up to an 8% risk for male breast cancer and up to a 7% risk for pancreatic cancer in men and women
Frequently asked questions about the BRACAnalysis® test
What can I expect during the testing process?
If you and your healthcare provider decide BRACAnalysis is right for you, a small blood or oral rinse sample is taken. This sample is then shipped directly to Myriad Genetic Laboratories. Results can be obtained from your health care provider in about two weeks.
Will my health insurance pay for BRACAnalysis testing?
Most insurance carriers cover genetic testing services for hereditary cancer. In fact, the average patient pays less than $100 coinsurance. Myriad helps you receive the appropriate coverage from your plan and be aware of your financial obligations prior to testing.
Can my health insurance coverage be impacted based on the results?
Federal laws (HIPAA and GINA) and laws in most states prohibit discrimination regarding employment eligibility, health benefits or insurance premiums based solely on genetic information. Additionally, it is Myriad’s policy that test results are disclosed only to the ordering healthcare professional or designee unless the patient consents otherwise.